1/8/2024 0 Comments Argen metals![]() ![]() Test high and low sample concentrations with its large dynamic range.Constantly monitor and reveal the kinetics of the sample evolution.Control the thermal, mechanical and chemical stressors for each cell.Swap in and out a sample from any cell without affecting the others.Finally, for samples undergoing degradation, ARGEN enables users to calculate both the decrease in molecular weight and changes in the rate.ĪRGEN is Different from Other High Throughput Light Scattering Instruments, ARGEN allows: Second, to detect and calculate the degree and rates of aggregation, ARGEN continuously monitors each sample throughout the entire aggregation process. No other testing platform has independent sample conditions. First, to test many configurations simultaneously, ARGEN has 16 independent sample holders, each with precise temperature and stirring stressor control. ARGEN, however, has three characteristics that differentiate it from other, similar technologies. To characterize the molecular weight and stability of polymers, proteins and other natural products, ARGEN uses Total Intensity Light Scattering, also referred to as Static Light Scattering, the widely accepted standard method. Simultaneously Tests 16 Independent Samples This technical note explains both how ARGEN quantitatively measures sample stability and the measurable benefits gained from using the instrument. This information is interpreted and used to provide detailed reports that reveal the samples degree and rate of mass change. The instrument collects and produces realtime sample aggregation information, identifies anomalous aggregation initiation delays and calculates the rate and total time that the process takes to reach a predetermined aggregation condition. Unparalleled amongst any other platform on the market, ARGEN users can remove, replace or extract aliquots from any of the 16 sample cells without interfering with any other ongoing measurement.ĪRGEN leverages the phenomenology known as Total Intensity Light Scattering (a.k.a Static Light Scattering) and continuously delivers essential qualitative and quantitative information about each sample. ARGEN applies temperature and stirring stressors independently to each of the 16 sample cells, replicating the conditions of and monitoring the sample in commonly encountered environments. Fluence Analytics ARGEN platform continuously measures the light scattering from 16 independent solutions to assess the pharmaceutical stability of therapeutic proteins and natural polymers.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |